Zinc supplement in reduction of relapses in children with steroid sensitive nephrotic syndrome. | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2014]

Author(s):

1. Afroze Ramzan Sherali: Department of Paediatric Nephrology, National Institute of Child Health (NICH), Karachi, Pakistan

2. Khemchand N. Moorani: Department of Paediatric Nephrology, National Institute of Child Health (NICH), Karachi, Pakistan

3. Saeed Hassan Chishty: Department of Paediatric Nephrology, The Kidney Centre Postgraduate Training Institute, Karachi, Pakistan

4. Shuja Iqbal Khan: Department of Paediatric Nephrology, National Institute of Child Health (NICH), Karachi, Pakistan

Abstract:

Objective: To determine whether Zinc supplementation could reduce relapse rate in children with nephrotic syndrome. study design: Randomized-controlled trial. place and duration of study: National Institute of Child-Health and The Kidney Centre, Karachi, from January 2008 to June 2009. Methodology: Sixty nephrotic children aged 2 - 15 years were selected. Baseline data including age, number of infections and relapses during pre and post study one year were recorded. Randomization was done to divide into Zinc group (Zg) to receive Zinc versus placebo (Pg) for 6 months. Relapses and infections were treated with standard therapy. T-test and chi-square tests were used to compare the mean values and proportions respectively with significance at p

Page(s): 110-113

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 24, Issue: 2, Year: 2014

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