Abstract:
A sample of 4210 subjects of both sexes aged 35-54 was examined, chosen at random from six regions of Croatia. An electrocardiogram at rest was performed in all subjects and changes analyzed by the Minnesota code. Forty-two (1. 0 %) of the saminees had a short P-R interval, while this finding together with a widening QRS complex and delta wave, was found in 0. 05 % of the examinees. During the period of the study, 0. 35 % of the subjects had a short P-R interval after three years, and of this number in 22 % the finding had disappeared in three years. 13 years after the first examination, there were more short P-R interval 3. 22% in females and 1. 96% in males. Three years after the first examination 0. 06% of the subjects had pre-excitation with a delta wave, and it appeared in one subject after three years. After 13 years those subjects did not appear for an examination, and the finding did not appear in any of other subjects during this period. Antigens of the HLA system were analyzed in 46 patients: WPW was found in 35 while 11 had LGL syndrome. Antigens of the HLA-A, HLA-B and HLA-DR locuses were determined by the microlympho cytotoxicity method. The results of the frequency of HLA system antigens were compared to the results in a Croatian population. There is increased frequency of HLA-A9 and HLA-B5 (p =0. 026 and 0. 0092) in the investigated population as a whole. The participation of HLA- A3 antigen is significantly less among patients (p = 0. 003), while the HLA-B14 antigen was not found in patients with pre-excitation (p=0. 03). Within 10 HLA-DR locuses, HLA-DR7 antigen was rather more frequently present, although this was not statistically significant (p = 0. 173).
Page(s):
2-7
DOI:
DOI not available
Published:
Journal: Pakistan Heart Journal, Volume: 25, Issue: 1--2, Year: 1992