Vitamin D supplementation in pregnant women and its effect on neonates in rural Jhelum | [Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23 • 2023]

Author(s):

1. Shaheena Anwar: Department of Biosciences, Salim Habib University, Karachi, Pakistan

2. M. Perwaiz Iqbal: Department of Biological and Biomedical Sciences, Aga Khan University, Karachi, Pakistan

3. Iqbal Azam: Community Health Sciences, Aga Khan University, Stadium Road, Karachi, Pakistan

4. Atif Habib: Centre of Excellence in Women and Child Health & Institute of Global Health & Development, Aga Khan University, Stadium Road, Karachi, Pakistan

5. Sajid B. Soofi: Centre of Excellence in Women and Child Health& Institute of Global Health & Development, Aga Khan University, Stadium Road, Karachi, Pakistan

6. Zulfiqar Ali Bhutta: Centre of Excellence in Women and Child Health& Institute of Global Health & Development, Aga Khan University, Stadium Road, Karachi, Pakistan; Centre for Child Global Health, Hospital for Sick Children, Toronto, ON, Canada

Abstract:

Vitamin D deficiency is a widespread health problem affecting people from all age groups. We conducted the first ever double blinded randomized control trial in Jhelum to answer a multitude of questions pertaining to vitamin D deficiency in the most fragile groups of our society; pregnant women and neonates. This nutritional study involved supplementing pregnant women during pregnancy and their neonates with vitamin D. Our observations indicated that most of the pregnant women and their newborns were vitamin D deficient (95% - 99% in rural Jhelum) at the time of recruitment. Supplementation with 4000 IU/d of women during pregnancy resulted in decrease in deficiency to 66.3% and increase in vitamin D levels in Jhelum study (Placebo = 29.8 ± 19.2 nmol/L vs. supplemented =44.6 ± 25.0 nmol/L, P<0.0001). Maternal supplementation also benefitted the neonates as the deficiency was lower and significantly different at the time of birth (placebo = 84.2% vs supplemented=54.7%, P<0.0001). Our observations indicated that most of the pregnant women and their newborns were vitamin D deficient regardless of their location (95%-99% in urban Karachi and rural Jhelum) at the time of recruitment. Supplementation with 4000 IU/d of women during pregnancy resulted in decrease in deficiency to 66.3% and increase in vitamin D levels in Jhelum study (Placebo = 29.8 ± 19.2 nmol/L vs. supplemented =44.6 ± 25.0 nmol/L, P<0.0001). Maternal supplementation also benefitted the neonates as the deficiency was lower and significantly different at the time of birth (placebo = 84.2% vs supplemented = 54.7%, P<0.0001).

Page(s): 58-58

DOI: DOI not available

Published: Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023

Keywords:

Vitamin D , maternal supplementation , Vitamin D supplementation , Control trial , Pregnant women

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