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The effects of low dose intravenous immunoglobulin on the outcome of Guillian Barre Syndrome.
Author(s):
1. Muhammad Tariq: Neurology Department, PIMS, Islamabad, Pakistan
2. Zahid Shakoor: Neurology Department, PIMS, Islamabad, Pakistan
3. Abdul-Shakoor: Neurology Department, PIMS, Islamabad, Pakistan
Abstract:
Twenty-two patients with Guillian Barre Syndrome admitted to the Department of Neurology, Pakistan Institute of Medical Sciences (PIMS) between November 1993 and March 1995 were given five grams of intravenous immunoglobulin daily for five days. Fourteen patients were male and 8 female. The duration of symptoms before the start of treatment was one to ten days. Fifty per cent of patients had no history of antecedent illness, While seven (31. 82%) had diarrhoea and 3 (13. 64%) had upper respiratory infection up to 2 weeks prior to the onset of GBS. Improvement was assessed on days 7 and 14, and 4 weeks after start of treatment. Fifteen patients (68. 18%) had grade 0-1 power at the start of the treatment. After one month of follow-up all patients had grade 2 power or more. Fifteen (68. 18%) had grade 4 and 5 power. Two patients died. This preliminary trial of low dose immunoglobulin indicates its effectiveness in GBS.
Page(s): 55-57
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 6, Issue: 1, Year: 1996
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