The use of selected Nigerian natural products in management of environmentally induced free radical skin damage. | [Pakistan Journal of Biological Sciences • 2005]

Author(s):

1. Odukoya A. Olukemi: Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine Campus, University of Lagos, PMB 12003, Sum Lere, Lagos, Nigeria

2. Jenkins M. Oluseyi: Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine Campus, University of Lagos, PMB 12003, Sum Lere, Lagos, Nigeria

3. Ilori O. Olukemi: Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine Campus, University of Lagos, PMB 12003, Sum Lere, Lagos, Nigeria

4. Sofidiya M. Olutoyin: Department of Pharmacognosy, Faculty of Pharmacy, College of Medicine Campus, University of Lagos, PMB 12003, Sum Lere, Lagos, Nigeria

Abstract:

This study investigated the effectiveness of natural extracts from honey, (Apis mellifera L. Apidae), cam wood (Pterocarpus osun Craib (Fabaceae) and Shea butter (Butyrospermum parkii G. Don, kotschy (Sapotaceae) incorporated for topical application in traditional cosmetic formulations in Nigeria to protect free radical induced skin damage. The effect of these samples on oxidative damage was assessed using the method of inhibition in lineolic acid peroxidation and vitamin E the predominant antioxidant in human skin as reference. Total antioxidants was measured as TAE (Total Antioxidant Equivalent). All the samples have antioxidant activity. The antioxidant activity (expressed as percent inhibition of oxidation) ranged from as high as 38.51-81.23% in honey depending on source since honey is produced from many different floral sources and subject to adulteration with syrup 73.65% in shea butter and 43.26% in cam wood. Antioxidant activity had a direct relationship with T AE (Total Antioxidant Equivalent). It is concluded that natural antioxidants could induce depigmenting effect and replace use of synthetics.

Page(s): 1074-1077

DOI: DOI not available

Published: Journal: Pakistan Journal of Biological Sciences, Volume: 8, Issue: 8, Year: 2005

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