FREQUENCY OF DEPRESSION IN FUNCTIONAL DYSPEPSIA PATIENTS PRESENTING TO A TERTIARY CARE HOSPITAL | [Journal of Postgraduate Medical Institute • 2016]

Author(s):

1. Abbas Khan Khattak: Department of Gastro-enterology, Lady Reading Hospital, Peshawar - Pakistan

2. Ahmad Nawaz Babar: Department of Gastro-enterology, Lady Reading Hospital, Peshawar - Pakistan

3. Moeen-Ul-Haq: Department of Gastro-enterology, Lady Reading Hospital, Peshawar - Pakistan

4. Muhammad Kamran Hassan: Department of Gastro-enterology, Lady Reading Hospital, Peshawar - Pakistan

Abstract:

Objective: To determine the frequency of depression in functional dyspepsia patients. Methodology: 247 patients satisfying Rome III definition of functional dyspepsia were assessed for depression applying NICE criteria for diagnosis of depression. Subjects with alarm features in history and examination were excluded as well as patients with any co morbid condition to reduce bias. The patients were put into various groups depending upon patient's predominant symptoms. The frequency of depression was assessed in dyspeptic patients. Furthermore strength of association was also checked between various variables and depression in dyspeptic patients. Results: Among 247 patients, 107 patients were female and 140 patients were male. Mean age and mean duration of illness was 35.84±11 years and 2.33±2.38 years respectively. Epigastric pain syndrome (EPS) was present in 28.9% of the patients, postprandial distress syndrome (PDS) was present in 28.5% of the patients and 42.7% had both the symptoms. Depression was diagnosed in 75.3% of functional dyspepsia patients. We found significant association between female gender and depression with a p value of 0.009. In univariate analysis significant association was again found between female gender and depression (OR 2.32, p value 0.01) but duration of the disease and dyspepsia group had no association. Conclusion: Frequency of depression was found high in functional dyspepsia patients. Therefore every functional dyspepsia patient should be thoroughly assessed for depression.

Page(s): 282-285

DOI: DOI not available

Published: Journal: Journal of Postgraduate Medical Institute, Volume: 30, Issue: 3, Year: 2016

Keywords:

Depression , Functional dyspepsia , Rome III criteria

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