TOTAL PHENOLIC-FLAVONOID CONTENTS, ANTI-LEISHMANIAL, ANTIMICROBIAL AND ANTIOXIDANT POTENTIALS OF PAKISTANI TEA BRANDS AND TEA PLANT CAMELLIA SINENSIS | [Pakistan Journal of Botany • 2022]

Author(s):

1. HINA REHMAN: Department of Biotechnology, Faculty of Biological Sciences, University of Malakand,Chakdara, Dir (L), KP,Pakistan

2. MUZAMIL SHAH: Department of Biotechnology, Quaid-i-Azam University,Islamabad,Pakistan

3. ZABTA KHAN SHINWARI: Department of Biotechnology, Quaid-i-Azam University, Islamabad Pakistan;Pakistan Academy of Sciences, Islamabad, Pakistan

4. WAQAR ALI: Department of Biotechnology, Faculty of Biological Sciences, University of Malakand,Chakdara, Dir (L), KP,Pakistan

5. NADIR ZAMAN KHAN: Department of Biotechnology, Faculty of Biological Sciences, University of Malakand,Chakdara, Dir (L), KP,Pakistan

6. MUHAMMAD AASIM: Department of Biotechnology, Faculty of Biological Sciences, University of Malakand,Chakdara, Dir (L), KP,Pakistan

7. NOOR SHAD BIBI: Department of Biochemistry, Abdul Wali Khan University,Mardan,Pakistan

8. MUHAMMAD AYAZ: Department of Pharmacy, Faculty of Biological Sciences, University of Malakand,Chakdara, Dir (L), KP,Pakistan

Abstract:

Tea is generally prepared by steeping the dried young leaves and buds of Camellia sinensis in a boiled water. Following water, tea is mostly consuming drink in the world. This research project was designed to evaluate different tea samples for various biological assays. Assays including antibacterial, antifungal, antileishmanial and antioxidant were carried out following standard procedures. Antimicrobial activities were include disc diffusion and micro broth dilution methods, while spectrophotometric method was used for antioxidant and anti-leishmanial assays. Our test samples exhibited considerable antibacterial activity against Pseudomonas aeruginosa and Staphylococcus aureus with MICs of 3.7 µg ml-1. Tapal and Tetly showed considerable inhibitory activities against R. solani with 64 ± 3.6 and 76 ± 45% inhibitions respectively at 10 mg ml-1 concentrations. Likewise, Lipton and Tapal showed 76 ± 54 and 76 ± 57% inhibitory activity against A. niger at 10 mg ml-1 concentrations. Tetly was most effective against L. tropica with IC50 of 293.9 µg/ml. Considerable antioxidant and phenolic, flavonoids contents might be responsible for these pharmacological activities and health benefits associated with the use the selected tea brands.

Page(s): 667-673

DOI: 10.30848/PJB2022-2(42)

Published: Journal: Pakistan Journal of Botany, Volume: 54, Issue: 2, Year: 2022

Keywords:

fungi , Camellia sinensis , leishmaniasis , Oxidative stress , Bacterial infections

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