A Antinociceptive activity of methanol extract of Solanum sisymbrifolium Lamk. | [Pakistan Journal of Biological Sciences • 2005]

Author(s):

1. J. A. Shilpi: Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

2. R. Rouf: Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

3. S. J. Uddin: Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

4. M. A. M. Sarker: Department of Pharmacology and Therapeutics, Khulna Medical College, Khulna, Bangladesh

5. A. R. Qamrunnah: Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208, Bangladesh

6. M. M. Ferdous: Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh

Abstract:

The antinociceptive activity of the methanolic extract of the whole plant of Solanum sisymbrifolium Lamk was investigated using acetic acid-induced writhing model in swiss albino mice. At the doses of 125, 250 and 500 mg kg-`body weight, the extract showed 44.19, 59.53 and 73.02% writhing inhibition, respectively in test animals which were comparable to that of standard drug aspirin (85.12%) and the results were statistically significant (p

Page(s): 1123-1125

DOI: DOI not available

Published: Journal: Pakistan Journal of Biological Sciences, Volume: 8, Issue: 8, Year: 2005

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