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An overview of hepatitis c viral infection and its management options.
Author(s):
1. Humaira Zafar: Microbiology Al Nafees Medical College Isra University, Islamabad Campus, Pakistan
2. Kiran Tauseef Bukhari:
3. Afroz S Kazi:
4. Abdul Qadar Khan Mohmmand:
Abstract:
Hepatitis C is an infectious disease of viral origin primarily affecting the liver, caused by the hepatitis C virus (HCV).The infection is usually subclinical/ asymptomatic, but chronic infection can lead to scarring of the liver and ultimately to cirrhosis leading to liver failure, hepato cellular carcinoma or life-threatening esophageal and gastric varices. The route of acquiring infection is by an exposure to blood or blood products. The virus persists in the liver in about 85% of those infected patients. Persistent infection can be treated with various anti viral medications like peginterferon and ribavirin. Theseare amongstthe current standard therapy. Overall cure rate is between 51-80%. Those who develop cirrhosis or liver cancer may require a liver transplant, and the virus universally recurs after transplantation.
Page(s): 43-47
DOI: DOI not available
Published: Journal: Isra Medical Journal, Volume: 4, Issue: 1, Year: 2012
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