Antibacterial and Hemolytic Activities of Brominated 2-Phenitidine Derivatives | [Proceedings of Pakistan Academy of Sciences • 2015]

Author(s):

1. Muhammad Athar Abbasi: Department of Chemistry, Government College University,Lahore,Pakistan

2. Amna Saeed: Department of Chemistry, Government College University,Lahore,Pakistan

3. Aziz-ur-Rehman: Department of Chemistry, Government College University,Lahore,Pakistan

4. Sabahat Zahra Siddiqui: Department of Chemistry, Government College University,Lahore,Pakistan

5. Kaniz Rubab: Department of Chemistry, Government College University,Lahore,Pakistan

6. Muhammad Shahid: Department of Chemistry and Biochemistry, University of Agriculture,Faisalabad,Pakistan

7. Fozia Anjum: Department of Chemistry, Government College University,Faisalabad,Pakistan

Abstract:

The present study describes the antibacterial and hemolytic activities of some brominated 2-phenitidine derivatives. These synthetic molecules were screened against selected bacterial strains, i.e., gram positive and negative using streptomycin as control. The cytotoxicity of these molecules was also tested using triton as reference. The study revealed that the analyzed molecules displayed moderate potential as antibacterial agents; however, these might serve as valued hemolytic agents.

Page(s): 233-237

DOI: DOI not available

Published: Journal: Proceedings of Pakistan Academy of Sciences, Volume: 52, Issue: 3, Year: 2015

Keywords:

cytotoxicity , antibacterial agents , hemolytic agents , 2phenitidine derivatives

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