Restorative potential of date fruit supplemented diet on serum lipidemic and oxidative stress biomarkers in rodent experimental modeling | [International Food & Nutrition Conference" August 18th-20th, 2022, University of Swat, Swat (Book of Abstracts) • 2022]

Author(s):

1. Kanza Aziz Awan: Department of Food Science and Technology, Faculty of Science and Technology, University of Central Punjab,Lahore,Pakistan

2. Masood Sadiq Butt: National Institute of Food Science and Technology Faculty of Food, Nutrition & Home Sciences University of Agriculture,Faisalabad,Pakistan

3. Hussan Munir: Al-Shaheer Foods, Karachi National Institute of Food Science and Technology, University of Agriculture Faisalabad,Pakistan

4. Sanabil: Department of Food Science and Technology, Faculty of Science and Technology, University of Central Punjab,Lahore,Pakistan

5. Amal Shaukat: Department of Food Science and Technology, Faculty of Science and Technology, University of Central Punjab,Lahore,Pakistan

6. Waleed Sultan: Department of Food Science and Technology, Faculty of Science and Technology, University of Central Punjab,Lahore,Pakistan

7. Aysha Imtiaz: National Institute of Food Science and Technology Faculty of Food, Nutrition & Home Sciences University of Agriculture,Faisalabad,Pakistan

Abstract:

Present research was designed to explore the functional worth Pakistani date cultivar (Zahidi) against atherogenic diet induced oxidative stress. Bioefficacy assessment of Zahidi fruit and extract was carried out via model feeding trial. The rats (Sprague dawley) were divided into two broad categories; one fed on normal diet, whereas the others were administered atherogenic diet to induce oxidative stress. The formulated groups were G1 (Normal diet), G2 (Date fruit + normal diet), G3 (Date extract + normal diet), G4 (Atherogenic diet), G5 (Date fruit + atherogenic diet) and G6 (Date extract + atherogenic diet). The results showed that date fruit reduced 3.65% serum cholesterol in normal rats, whereas 15.14% in atherogenic rats, while, the date extract treatment resulted in 4.49 and 18.55% reduction in normal and atherogenic rats, respectively. Low-density lipoprotein (LDL) cholesterol reduced by 8.66 and 11.55% in date fruit and date extract fed normal rats, respectively. Whilst, 21.05 and 25.98% reductions were noted in the atherogenic groups fed on date fruit and date extract containing diets, respectively. To assess the extent of cardiac risk in the subjects, several atherogenic ratios were calculated based on the serum lipid parameters. The analysis showed that atherogenic diet groups were at higher risk than the normal ones and date fruit and extract containing functional diets effectively ameliorated the elevated risk ratios. The date fruit and extract-based diets intensified serum superoxide dismutase (SOD) and catalase (CAT) levels throughout the study up to 29.05 and 27.99%, respectively. Date fruit effectively lowered lipid peroxidation by 13.64 and 33.67% in normal and atherogenic rats, respectively. Conclusively, date fruit and extract treatment proved effectual in modulating the serum lipid profile and effectively restored the SOD and CAT levels alongside reducing the lipid peroxidation.

Page(s): 46-46

DOI: DOI not available

Published: Journal: International Food & Nutrition Conference" August 18th-20th, 2022, University of Swat, Swat (Book of Abstracts), Volume: 1, Issue: 1, Year: 2022

Keywords:

lipid peroxidation , atherogenic index , Serum cholesterol , Endogenous enzymes , Atherogenic diet , Zahidi date fruit

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