Synthesis; characterization; theoretical calculations and anti-tumor study of 2-Aminopyridine trifluorotitanium (IV) complex. | [Journal of Chemical Society of Pakistan • 2015]

Author(s):

1. Fahmideh Shabani: Chemistry Department, Science faculty, Arak Branch, Islamic Azad University, Arak, Iran

2. Saeed Jameh Bozorghi: Chemistry Department, Science faculty, Hamedan Branch, Islamic Azad University, Hamedan, Iran

3. Mozhgan Sheykhpoor: Department of cellular and molecular biology, Research center of new Technologies in life science Engineering, University of Tehran, Iran

Abstract:

A new titanium compound that is 2-Aminopyridine trifluorotitanium (IV) complex was synthesized and identified. This Complex was prepared through the reaction of 2-Amino pyridine and titanium tetrafluoride salt of in acetonitrile. Identification and Characterization of complex was performed by elemental analysis and spectroscopic methods. Structural and spectroscopic study of the mentioned complex was carried out at DFT- B3LYP/6-311G level of theory. This new compound was used to biological studies; and its anticancer properties against the two types of cancer cells such as k562 (human chronic myeloid leukemia) and Jurkat (human T lymphocyte carcinoma) was revealed.

Page(s): 1135-1142

DOI: DOI not available

Published: Journal: Journal of Chemical Society of Pakistan, Volume: 37, Issue: 6, Year: 2015

Keywords:

Keywords are not available for this article.

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views