16 a hydroxy-(-)-kauran-19-oic acid: an antibacterial diterpene from sweet apple (annona squamosa l., annonaceae). | [International Journal of Pharmacology • 2005]

Author(s):

1. Mazdida Sulaiman: Foundation Center of Sciences, University of Malaya, Malaysia

2. Hassan Hamimah: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

3. Yusof Mohd: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

4. Ta Siang Au: Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

5. Christophe Wiart: Department of Pharmacy, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

Abstract:

The methanolic extract of sweet apple (Annona squamosa L.) showed a good antibacterial activity against both ATCC and clinical strains of Staphylococcus aureus and Streptococcus pneumoniae. 16 α Hydroxy-(-)-kauran-l9-oic acid, was identified as the compound responsible for the antibacterial activity of this plant.

Page(s): 296-298

DOI: DOI not available

Published: Journal: International Journal of Pharmacology, Volume: 1, Issue: 3, Year: 2005

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