A PROFILE OF PLASMA CONCENTRATION OF ADIPONECTIN IN PRIMARY SCHOOL CHILDREN IN DERA ISMAIL KHAN | [Journal of Postgraduate Medical Institute • 2014]

Author(s):

1. Muhammad Ramzan: Department of Biochemistry,Peshawar Medical College,Peshawar, Pakistan.

2. Irshad Ali: Department of Chemistry,Gomal University, Dera Ismail Khan, Pakistan

3. Muhammad Haris Ramzan: Department of Physiology,Institute of Basic Medical Sciences,Khyber Medical University, Peshawar, Pakistan.

4. Faiqah Ramzan: Gomal Centre of Biochemistry and Biotechnology, Gomal University, Dera Ismail Khan , Pakistan.

5. Faiza Ramzan: Department of Microbiology,Quaid-e-Azam University,Islamabad., Pakistan

Abstract:

Objective: The objective of the present study was to determine the plasma Adiponectin concentration in primary school children 6-11 years and to eval[1]uate negative association of Adiponectin in obese children. Methodology: This cross sectional study was carried out in the Department of Chemistry, Gomal University, Dera Ismail Khan from June 2007 to August 2010. A total number of 1336 primary school children were examined in the Municipality area of Dera Ismail Khan and excluding those suffering from chronic health problems. Height (m), weight (kg) of each child was taken and BMI was calculated according to Quatelet’s Index. Body mass Status was also calculated through CDCs? Growth Charts 2002, 2-20years for children to have percentile for each school child. School children with ≥5th percentile were de[1]clared normal weight and the ones having ≥95th percentile as obese. 83 school children were randomly selected among 1336 children with 23 (27.71%) nor[1]mal weight and 60 (72.28%) as obese ones. Gender wise distribution of the sample was 48 (57.83%) boys and 35 (42.16%) as girls. Fasting plasma adi[1]ponectin concentration was determined by ELIZA method. Results: Mean plasma adiponectin concentration in normal weight children was noted as 21.38µg/ml (P = 0.013) and 20.89µg/ml (P = 0.011) in boys and girls respectively. The observed, mean plasma adiponectin level in obese children was 20.38µg/ml (P =0.0130) and 25.56µg/ml (P = 0.0016) in boys and girls respectively. Conclusion: Significant difference in plasma adiponectin concentration was observed between normal weight and obese girls

Page(s): 33-36

DOI: DOI not available

Published: Journal: Journal of Postgraduate Medical Institute, Volume: 28, Issue: 1, Year: 2014

Keywords:

school children , Obesity , adiponectin

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