Do Mortality and Acute Respiratory Distress Syndrome due to COVID-19 are related to 1085 P J M H S Vol. 14, NO. 3, JUL - SEP 2020 Do Mortality and Acute Respiratory Distress Syndrome due to COVID-19 are related to Pneumonia or Angioedema like illness? | [Pakistan Journal of Medical and Health Sciences • 2020]

Author(s):

1. ELHASSAN HUSSEIN ELTOM: Department of Pharmacology, Faculty of Medicine, Northern Border University,Arar, KSA,

2. HUSHAM O.ELZEIN: Department of Medical Laboratory, Faculty of Applied Medical Sciences, Northern Border University,Arar,Saudi Arabia ;Faculty of medical laboratory science, University of Science and Technology,Khartoum,Sudan

Abstract:

Coronavirus disease 2019 (COVID-19) outbreak, arisen in Wuhan, China. It is very series disease.Started with pneumonia of unknown etiology whichhave been reported to the World Health Organization (WHO) on 31 December 2019. Novel coronavirus (2019-nCov) was identified and isolated by Chinese health authorities on 7 January 2020, and it was sharing the same receptor, Angiotensin-converting enzyme 2 (ACE2) as SARSCoV,ACE2 RNA expression profile in the normal human lung and ACE2 virus receptor expression is concentrated in a small population of type II alveolar cells. This study highlights important questions regarding the pathophysiology, and treatment options of COVID-2019; firstly, is the dry cough associated with the course of illness of COVID-2019 due to the overproduction of bradykinin? Secondly, is the ARDS and mortality associated with COVID-2019 are due to pneumonia or angioedema like illness?

Page(s): 1085-1086

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical and Health Sciences, Volume: 14, Issue: 3, Year: 2020

Keywords:

COVID2019 , AT2Receptor , Angioedema like illness

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