Vitreo-macular Interface Abnormalities in Diabetic and Non-Diabetic Patients Using Optical Coherence Tomography | [Pakistan Journal of Ophthalmology • 2020]

Author(s):

1. Uzma Hamza: Department of Ophthalmology, Allama Iqbal Medical College, Jinnah Hospital, Lahore,Pakistan

2. Waqas Asghar: Department of Ophthalmology, Allama Iqbal Medical College, Jinnah Hospital, Lahore,Pakistan

3. Qasim Lateef Chaudhry: Department of Ophthalmology, Allama Iqbal Medical College, Jinnah Hospital, Lahore,Pakistan

4. Muhammad Hassaan Ali: Department of Ophthalmology, Allama Iqbal Medical College, Jinnah Hospital, Lahore,Pakistan

5. Sana Jahangir: Department of Ophthalmology, Allama Iqbal Medical College, Jinnah Hospital, Lahore,Pakistan

Abstract:

Purpose: To study the frequency of vitreomacular interface abnormalities (VIAs) in diabetic and non-diabetic patients presenting in a tertiary care hospital. Study Design: Comparative cross-sectional study. Methods: The frequency of vitreomacular interface abnormalities (VIAs) was assessed among 278 patients, who presented in outpatient department of our hospital. Patients were categorized into diabetic and non-diabetic groups on the basis of hemoglobinHbA1c. Patients with altered macular reflex on slit lamp examination underwent spectral domain (SD) optical coherence tomography (OCT) of macula to determine VIAs. Results: There were 278 patients in the study with mean age 59.7 ± 11.7(range: 40 - 65) years and male to female ratio of 1:1.06. Prevalence of VIAs was observed to be higher among diabetic patients than non-diabetics in all age groups (p-value < 0.05). Overall frequency of different VIAs was found to be 10.7% for epiretinal membrane, 6.4% for posterior vitreous detachment, 6.1% for macular edema/macular cyst, 4.3% for vitreomacular traction, 1.8% for full thickness macular holes and 0.71% for partial thickness macular holes. Macular edema/macular cystwas the most common. VIA was more commonly observed in diabetic patients (17.2%). Except for ERM, all lesions of VIAs were significantly more prevalent in females as compared to males. Conclusion: VIAs are found in significantly larger number in diabetics compared to non-diabetic patients. Female gender with advancing age is associated with a higher frequency of VIAs.

Page(s): 282-286

DOI: 10.36351/pjo.v36i3.1018

Published: Journal: Pakistan Journal of Ophthalmology , Volume: 36, Issue: 3, Year: 2020

Keywords:

Vitreomacular traction , Vitreomacular interface abnormalities

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