Transabdominal Ultrasonography in Staging of Wilms Tumor. | [Pakistan Armed Forces Medical Journal • 2018]

Author(s):

1. Humaira Ali: HITEC Institute of Medical Sciences Taxila Pakistan,

2. Uzma Abdullah: Margalla General Hospital Rawalpindi, Pakistan

3. Rahat Shahid: Pakistan Naval Ship (PNS) Hafeez Islamabad Pakistan,

4. Khadija Qamar: Army Medical College/National University of Medical Sciences (NUMS) Rawalpindi Pakistan

Abstract:

Objective: To determine the sensitivity and specificity of transabdominal ultrasonography (US) in staging of Wilms tumor, taking transabdominal contrast enhanced computed tomography (CT) of abdomen as gold standard. Study Design: Cross sectional/validation study. Place and Duration of Study: Radiology department, Children Hospital, Pakistan Institute of Medical Sciences, Islamabad, from Apr 2006 to Mar 2007. Material and Methods: Thirty patients presenting with Wilms tumor underwent transabdominal ultrasound and CT abdomen with contrast for staging. All of them were evaluated for age, gender, presenting complaints, signs and symptoms. As patients were children so consent was taken from their parents. X-ray chest of all of the patients was done to exclude pulmonary metastasis. Results: For stage-I: Ultrasound correctly staged 10 out of 15 cases of stage-I (66.6%) and over staged 5 out of 15 cases of stage-I (33.3%). For stage-II: Ultrasound correctly staged 2 out of 8 cases of stage-II (25%) and incorrectly staged 6 out of 8 cases of stage-II (75%). For stage-III: Ultrasound correctly staged 4 out of 7 cases of stage-III (57%) and incorrectly staged 3 out of 7 cases of stage-III (43%). Conclusion: In children, ultrasound abdomen plays a vital role in cases of renal tumors for differential diagnosis, staging, monitoring of therapy and surgical planning. Diagnostic information obtained from CT and ultrasound examinations are complementary in many instances, however, computed tomography (CT) has been shown to be superior to ultrasound (US) in this regard.

Page(s): 339-344

DOI: DOI not available

Published: Journal: Pakistan Armed Forces Medical Journal, Volume: 68, Issue: 2, Year: 2018

Keywords:

Keywords are not available for this article.

References:

[1] ThomasKE,OwensCM, 2003.Edi),Text book of radiology and imaging 1 849 -84

[2] YoungJR,MargolisD,SaukS,PantuckAJ,SayreJ,RamanSS, 2013.Clear cell renal cell carcinoma: discrimination from other renal cell carcinoma subtypes and oncocytoma at multiphasic multidetector CT,Radiology 267 444 -53

[3] RamamurthyNK,MoosaviB,McInnesMD,FloodTA,SchiedaN., 2015.Multiparametric MRI of solid renal masses: pearls and pitfalls,Clin Radiol 70 304 -316

[4] GurelS,NarraV,ElsayesKM,SiegelCL,ChenZE,BrownJJ, 2013.Subtypes of renal cell carcinoma: MRI and pathological features,Diagn Interv Radiol 19 304 -311

[5] MotzerRJ,AgarwalN,BeardC,BhayaniS,BolgerGB,CarducciMA, 2011.Kidney cancer,J Natl Compr Canc Netw 9 960 -77

[6] SiegelRL,MillerKD,JemalA, 2015.,CA Cancer J Clin 65 5 -29

[7] BylerTK,BratslavskyG, 2014.Hereditary renal cell carcinoma: genetics, clinical features, and surgical considerations,World J Urol 32 623 -30

[8] LockhartME,SmithKJ,KenneyPJ,LeeJKT,SagelSS,StanleyRJ,HeikenJ P., 2006.The Kidney and Ureter,Computed Body Tomography with MRI Correlation. 4th ed. Missouri. Lippincott Williams & Wilkins 1233 -99

[9] RickettsCJ,ShuchB,VockeCD,MetwalliAR,BratslavskyG,MiddeltonL, 2012.Succinate dehydrogenase kidney cancer: An aggressive example of the Warburg effect in cancer,J Urol 188 2063 -71

[10] JiangJ,ChenY,ZhouY,ZhangH, 2010.Clear cell renal cell carcinoma: contrast-enhanced ultrasound features relation to tumor size,Eur J Radiol 73 162 -67

[11] CornelisF,TricaudE,LasserreAS,PetitpierreF,BernhardJC,Le BrasY, 2015.Multiparametric magnetic resonance imaging for the differentiation of low and high grade clear cell renal carcinoma,Eur Radiol 25 24 -31

[12] KabalaJE,RoobottomC., 2003.David Sutton (edi). Text book of radiology and imaging vol-II. 7th ed, 929 -87

[13] Mueller-LisseUG,Mueller-LisseUL, 2010.Imaging of advanced renal cell carcinoma,World J Urol 28 253 -61

[14] LassauN,ChebilM,ChamiL,BidaultS,GirardE,RocheA, 2010.Dynamic contrast-enhanced ultrasonography (DCE-US): a new tool for the early evaluation of antiangiogenic treatment,Target Oncol 5 53 -8

[15] BellmuntJ,PuenteJ,Garcia de MuroJ,LainezN,RodríguezC,DuranI. SEOM, 2014.clinical guidelines for the treatment of renal cell carcinoma,Clin Transl Oncol 16 1043 -50

[16] JemalA,SiegelR,WardE, 2010.,CA Cancer J Clin 60 277 -300

[17] SalagierskiM,SalagierskiMS,Salagierska BarwińskaA, 2010.Radiofrequency ablation in kidney tumour management: A method of real-time monitoring,Scand J Urol Nephrol 44 84 -90

[18] LyrdalD,AnderssonM,HellströmM,SternalJ,LundstamS, 2010.Ultrasound-guided percutaneous radiofrequency ablation of small renal tumors: clinical results and radiological evolution during follow-up,Acta Radiol 51 808 -18

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