Therapeutic potential of bacteriocin like inhibitory substances against different disease conditions | [Pure and Applied Biology • 2021]

Author(s):

1. Azka Qadeer: Institute of Microbiology, University of Agriculture, Faisalabad, Punjab, Pakistan

2. Ashiq Ali: Department of Pathology, University of Agriculture, Faisalabad, Punjab, Pakistan

3. Nishat Zafar: Institute of Microbiology, University of Agriculture, Faisalabad, Punjab, Pakistan

4. Rabia Kanwar: Institute of Microbiology, University of Agriculture, Faisalabad, Punjab, Pakistan

5. Sidra Altaf: Institute of Physiology Pharmacology and Pharmacy University of Agriculture, Faisalabad, Pakistan

6. Muhammad Bilal: Department of Microbiology, Government College University Faisalabad, Pakistan

7. Sana Fatima: National Health Services Regulation and Coordination, Pakistan Institute of Medical Sciences, Islamabad,Pakistan

8. Mehak Gul: Department of Microbiology and Molecular Genetics, University of Punjab, Pakistan

9. Ghaniya Arif Ahmed: Department of Microbiology, Government College University Lahore, Pakistan

Abstract:

Bacteriocin like inhibitory substance produced in many starter cultures and milk products has the significant potential to improve the quality of diverse edible food stuffs. Many authors confirmed that the Nisin produced by many lactic acid bacteria used in many food items to stop L. monocytogenes. The data resulted from the antimicrobial substances establish determined that the peptides existence towards indicator bacteria might be considered as BLIS because they have the bacteriocin like compounds, but they did not until now been characterized for encoding nucleotide sequences and amino acid. Antibiotic resistance result from the extreme utilizing of therapeutic agents in animals and humans is an international issue. This concern has diverted the concentration of researchers to discover another key answer for these antimicrobial agents. Bacteriocin-like inhibitory compounds are currently considered as the new substitute for antibiotics to cure numerous diseases and infections. Bacteriocin like compounds obtained from Gram-positive bacteria is present in scientists' deliberation due to their various range of antimicrobial action. This review focuses on the therapeutic potential of bacteriocin-like inhibitory substances against different disease conditions.

Page(s): 1484-1493

DOI: 10.19045/bspab.2021.100154

Published: Journal: Pure and Applied Biology, Volume: 10, Issue: 4, Year: 2021

Keywords:

Antibiotic resistance , Inhibitory substances , bacteriocin , Therapeutic agents

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