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Effect of in utero ultrasound exposure (5MHz) on developing rat testes.
Author(s):
1. Muhammad Suhail: Department of Anatomy, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan
2. Muhammad Zubair: Department of Anatomy, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan
3. Mustafa Raza Kazmi: Department of Anatomy, Shaikh Zayed Postgraduate Medical Institute, Lahore, Pakistan
Abstract:
The frequent use of diagnostic ultrasound in various branches of medicine, particularly in Obstetrics & Gynaecology has led to consider the safety of ultrasound waves during gestation. Since the embryos and fetuses are at risk for any teratological insult, ultimately leading congenital abnormalities, therefore this study was designed to see the bioeffects of 5 MHz frequency ultrasound waves on the development of testes. Two experimental groups S2 & S3 received 6 & 9 exposures of ultrasound waves, respectively of 5 minutes duration each time, during their entire gestation. After parturition the male offsprings were selected and were grown to puberty and then dissected. Their testes were removed and were studied for gross features. The mean testicular weight in control (subgroup S,) was 2.64±0.29, while in experimental subgroups S2 & S3 was 1.99±0.29 & 1.8±0.29, respectively. The relative tissue weight index in control (group S,) was 1.64±0.18, while in the experimental groups (S2 & S3) was 1.15±0.08 and 1.1±0.1, respectively. These results showed statistically significant reduction of mean testicular weight and relative tissue weight indices as compared to control (p0.05). The conclusion drawn from this study is that ultrasound exposure of 5 MHz produced reduction in mean testicular weight but increased number of exposures did not produced more severe effects.
Page(s): 1-5
DOI: DOI not available
Published: Journal: Proceedings of sheikh zayed postgraduate medical institute, Volume: 17, Issue: 1, Year: 2003
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