Variation of total and differential count of Leukocytes and increment in the number of young Neutrophils in different trimesters of pregnancy. | [Pakistan Journal of Medical Sciences • 2005]

Author(s):

1. T. Pramanik: Department of Clinical Physiology, Nepal Medical College, Jorpati, Kathmandu, Nepal

2. A. Ghosh: Department of Clinical Physiology, Nepal Medical College, Jorpati, Kathmandu, Nepal

3. H. Tuladhar: Department of Obstetrics & Gynecology, Nepal Medical College, Jorpati, Kathmandu, Nepal

4. P. Pradhan: Department of Obstetrics & Gynecology, Nepal Medical College, Jorpati, Kathmandu, Nepal

Abstract:

Objective: Tofind out the variation of total and differential count of eucocytes and young neutrophils in young non-pregnants and pregnant ladies of different trimesters. Setting: Nepal Medical College, Jorpati, Kathmandu, Nepal Design: Total and differential count of leukocytes were performed and percentage of young band forms among the neutrophils was determined in young non pregnant women and in young pregnant ladies in different trimesters. Results: Increase in the number of total leukocyte, neutrophil and monocyte along with decrease in the number of lymphocytes is noticed in all the three trimesters of pregnancy in comparison to those of non pregnant counterparts. Eosinophil count increases significantly in the 2nd trimester of pregnancy in comparison to non pregnant women. The number of young band forms among the neutrophils having more myeloperoxidase (the main bactericidal system in neutrophil) increases with the advancement of pregnancy. Conclusions: The weakened specific immunity of the maternal host (due to decrease of IgA, IgG and IgM in pregnancy) is compensated at least partly by non specific immunity exerted by young neutrophils and other WBCs like eosinophils and monocytes.

Page(s): 44-46

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Sciences, Volume: 21, Issue: 1, Year: 2005

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