Abstract:
Objective: The aim of this research work was the assessment of the association of vitiligo disease and DED (Dry Eye Disease) with the help of different objective parameters. Methodology: This research work was performed on 30 patients of vitiligo and 31 patients present with refractory complaints of non-complicated nature. Ophthalmologic examination was carried out on all the patients which included Schirmer Test-I, FBU (Fluorescein Break-up Time) and CFS (Cornea Fluorescein Staining). Different OSDI means (Ocular Surface Disease Index) were in utilization for the assessment of the dry eye status. Results: Participants of both groups were same about the gender and age distribution. The patients of the vitiligo disease group were present with high scores of OSDI (24.10±13.70 versus 12.50±3.20, T-test, P<.0010), shorter FBU scores (5.6±2.7 versus 7.60±2.20, Mann's-Whitney U test, P=.0050) and higher positivity of CFS (18/30 versus 3/31, by Chi-square test, P<.0010) as related to the patients of control group. The patients of both groups were present with much similar results regarding the Schirmer and MGD outcomes. There was presence of periocular involvement in 44.68% (n: 14) patients of vitiligo disease. Thorough analysis within the patients of vitiligo showed that the values of Schirmer test and FBU were much less in the patients present with peri-ocular involvement, MGD status and scores of OSDI were much similar. Conclusion: This research work concluded that there is a possible correlation of vitiligo and DED. The tools of diagnosis for dry eye complication are in decent association with one another. For follow-up and diagnostic purposes, OSDI questionnaire seems much pragmatic.
Page(s):
1367-1369
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Medical and Health Sciences, Volume: 16, Issue: 1, Year: 2022
Keywords:
diagnosis
,
Metabolism
,
Dry eye disease
,
Refractory
,
Vitiligo
,
Hypochromic