Can we really treat thalassemia major? | Proceedings of Pakistan Academy of Sciences 2013

Author(s)

Rashid A Seyal Department of Medicine, Seyal Medical Centre, LMQ Road, Multan, Pakistan

Siraj M Tareen Department of Medicine, Nishtar Medical College, Multan, Pakistan

Hayat M Awan Air University, Multan Campus, Pakistan; Department of Medicine, Seyal Medical Centre, LMQ Road, Multan, Pakistan

Abstract

Plant species have proven to be an important source of treatment in different diseases, in particular certain malignant tumors. The cytotoxic efficacy of Fagonia cretica has long been a subject of interest. This particular interest in a patient of breast cancer helped us to ascertain the efficacy of this herbal plant in Thalassemia. In initial testing, we obtained encouraging results by using dried aerial parts of the whole plant. It obligated upon us a detailed study of the plant in Thalassemia. A powder of the dried aerial parts of the whole flowering plant was given in doses of 120 mg/kg body weight. The hematological and clinical results in nine Thalassemia Major group, showed a decrease of the Hb F from 97.45 to 10.82% and increase of Hb A from 0.33 to 85.5% (P

Publication Details

Page(s) 315-325

DOI DOI not available

Published Journal: Proceedings of Pakistan Academy of Sciences, Volume: 50, Issue: 4, Year: 2013

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