Abstract:
Background: Breast cancer is the most common malignancy in Pakistani women; more than 4000 women are affected by this systemic disease annually. .Exceeding number of patients (median 49.6) have grade III invasive ductal carcinoma (IDC). Aim: To observe the trend of breast cancer in patients presenting to a tertiary care institution of Punjab. Method: An observational study was conducted at Surgical Unit-I of Services Hospital, Lahore. A retrospective review of medical record was done for the patients presenting to the outpatient department and admitted for surgery between January 2015-December 2016.Information was compiled for the variables which included age,gender,family history, menopausal status, status of neo adjuvant chemotherapy (NAC) and histology and grade of tumour. Results:During a period of 2 years a total of 37 patients of breast cancer were admitted in the Surgical Unit-I of Services hospital Lahore for modified radical mastectomy with axillary lymph node dissection (ALND) after a diagnosis was made by trucut biopsy and triple assessment was done. Mean age at presentation was found to be 49±11.7 years (Median=45).Average length of hospital stay was 6.25± 3.51 days. The average of NAC cycles received was found to be 5.42±3.15 (Median=4).Highest incidence of locally advanced breast cancer was found in the women of age group between 41-60 years. Family history of breast cancer was positive in only one of the patients which makes 2.86%. NAC was given to 40% of the patients and 60% did not receive NAC. As far as the stage of the disease was concerned; 77.14 % of patients had stage IIIB and 22.86 % had stage IIB disease. Disease recurrence was noted for 5.71 % of the patients which presented as metastatic disease within one year and both died in the same year. Conclusion:In our limited data of a 2 year period we have found that LABC is more common in our hospital with good one year outcome.LABC is more prevalent in younger patients. Breast cancer in our patients does not seem to relate to parity, marital status, history of breast feeding and family history.
Page(s):
317-319
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Medical and Health Sciences, Volume: 14, Issue: 1, Year: 2020