Author(s):
1. Muhammad Khalid:
Department of Pediatric Medicine, Nishtar Medical University, Multan, Pakistan
2. Ghulam Mustafa:
Department of Pediatric Medicine, Nishtar Medical University, Multan, Pakistan
3. Muhammad Abu Talib:
Department of Pediatric Medicine, Nishtar Medical University, Multan, Pakistan
4. Ejaz Ahmad:
Department of Pediatric Medicine, Nishtar Medical University, Multan, Pakistan
Abstract:
Objective: The study aimed to compare the serum vitamin D levels in infants1-6 months of age with acute lower respiratory tract infection with
healthy controls. Study Design: The present study was unmatched case-control (1:1) study. Place and Duration of Study: This study was undertaken at Pediatric Department of Nishtar Medical University, Multan from 7th August 2021 – 7th February 2022. Material and Methods: Infants 1 – 6 months age, of either gender were enrolled through consecutive sampling. Cases (n=30) were admitted infants with acute lower respiratory tract infection and controls (n=30) were healthy infants visiting immunization center. Venous blood samples were collected from both mothers and infants for estimating vitamin D levels. Descriptive statistics were run and mean vitamin D levels were compared through t-test.
Results: Median age was 2.5 months (range 1-6) and 71% (n=43) of the infants were male. Prevalence of exclusive breastfeeding was only
48% (n=29) and compared to healthy infants it was more in sick ones (31% vs. 69%, p-value 0.004). Majority of the infants (76.7%, n= 46)
had suboptimal vitamin D status and vitamin D levels did not differ among cases and controls (30.8 ± 21.6 vs. 29.9 ± 22.1 nmol/L, p-value
0.91). However, cases on exclusive breastfeeding had significantly lower vitamin D levels compared to the controls (22.2 ± 14.2 vs. 41.3 ±
28.9 nmol/L, p-value 0.02). Conclusion: High prevalence of Vitamin D deficiency and low level of exclusive breastfeeding was evident in our study. Cases on exclusive breastfeeding had significantly lower vitamin D levels compared to the controls.
Page(s):
373-378
DOI:
DOI not available
Published:
Journal: Pakistan Paediatric Journal, Volume: 46, Issue: 4, Year: 2022
Keywords:
Vitamin D Deficiency
,
Breastfeeding
,
Vitamin D
,
infant
,
Respiratory tract infection
References:
References are not available for this document.
Citations
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