A neonate with hand, foot, and mouth disease complicated with brainstem encephalitis and pulmonary edema: A complete recovery. | [Pakistan Journal of Medical Sciences • 2014]

Author(s):

1. Shi-Jie Guo: Department of Neonatology, The First Hospital of Jilin University, Changchun 130021, China

2. Dong-Xuan Wang: Department of Ultrasonic Diagnosis, The First Hospital of Jilin University, Changchun, China

3. Chun-Lai Dai: Department of Radiology, The First Hospital of Jilin University, Changchun 130021, China

4. Hui Wu: Department of Neonatology, Hui Wu, MD, Department of Neonatology, The First Hospital of Jilin University, No.71 Xinmin Street, Changchun 130021, China

Abstract:

Hand, foot, and mouth disease (HFMD) with serious complications and fatal cases have been reported over the last decade worldwide. The authors report a rare case of HFMD in a neonate complicated with brainstem encephalitis and pulmonary edema. She had fever, lethargy, dyspnea. Physical examination revealed shock signs, fine rales on both lungs, absent Moro reflex. The patient had a rapidly progressive course with seizures, coma, no spontaneous breathing, chemosis. There were some vesicles on left sole and red maculopapular rashes on perianal skin. She had a history of exposure to HFMD. Fecal sample was positive for EV71 RNA by real-time PCR. Chest X-rays showed bilateral pulmonary infiltrates. MRI of the brain showed significant hypointensity in the brainstem on T1WI and hyperintensity on T2WI. She recovered well. This case highlights severe HFMD in neonates is rare. Medical history and physical examination are important in making diagnosis.

Page(s): 917-919

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Sciences, Volume: 30, Issue: 4, Year: 2014

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