Visceral leishmaniasis among children presenting with pancytopenia | [Annals of the Pakistan Institute of Medical Sciences • 2019]

Author(s):

1. Khawaja Tahir Aziz: Pediatric Department, Azad Jammu and Kashmir Medical College Muzaffarabad, Pakistan

2. Naheem Ahmed: Pediatric Department, Azad Jammu and Kashmir Medical College Muzaffarabad, Pakistan

3. Muhammad Mateen Khan: Pediatric Department, Azad Jammu and Kashmir Medical College Muzaffarabad, Pakistan

4. Rashada Bibi: Radiology Department, Azad Jammu and Kashmir, Medical College Muzaffarabad, Pakistan

5. Abdul Rauf: Pediatric Department, Azad Jammu and Kashmir, Medical College Muzaffarabad, Pakistan

Abstract:

Background: Pancytopenia may either arise from a production defect of hematopoietic progenitors or from the cellular function's peripheral destruction because of infection, hypersplenism or immune-mediated damage. Visceral leishmaniasis (VL), is among the chronic parasitic infections globally, which affects millions of people recently, has been found to be increasing in frequency among Pancytopenia patients. Objective: To determine the frequency of visceral leishmaniasis among children presenting with pancytopenia at Pediatric Department, Azad Jammu and Kashmir Medical College Muzaffarabad. Methodology This cross sectional study was conducted at the Department of paeds SKBZ/ CMH, Muzaffarabad. The study duration was 6 months from June 2018 to December 2018. All children with pancytopenia of either gender were enrolled. After getting demographic information, all the cases underwent bone marrow sampling to assess the Visceral Leishmaniasis. All the data was collected by self-made proforma. Results: Total 75 patients were studied; their mean age of patients was 6.74±3.14 years. Males were in majority 67.69% and 32.31% were females. Leishmaniasis was found 15.38% of the cases. Leishmaniasis was statistically insignificant according to age and gender; p-values were quite insignificant. Conclusion: It is concluded that the visceral leishmaniasis in children with pancytopenia was 15.38%.

Page(s): 154-157

DOI: DOI not available

Published: Journal: Annals of the Pakistan Institute of Medical Sciences, Volume: 15, Issue: 4, Year: 2019

Keywords:

Visceral leishmaniasis , pancytopenia

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