Topical and oral Anti-inflammatory formulations of Ficus racemosa (Leaf) Extracts. | [Hamdard Medicus • 2007]

Author(s):

1. Mukul Tailang: Department of Pharmacy, Faculty of Technology, Barkatullah University, Hoshangabad Road, Bhopal, India

2. Damodar Goupale: Department of Pharmacy, Faculty of Technology, Barkatullah University, Hoshangabad Road, Bhopal, India

Abstract:

The anti-inflammatory activity of petroleum ether and alcoholic extracts of Ficus raceinosa leaves has been reported. The oral and topical formulations of these extracts were developed and evaluated for their activity against carrageen n induced rat paw oedema. The effects of preparations were observed for 6 hrs. Topical formulation in the concentration of 10% w/w petroleum ether extract exhibited maximum anti-inflammatory effect; hat is 67.96% at the end of 3 hrs. In case of oral suspension formulations the doses 100 mg/kg body weight of petroleum ether and alcoholic extract exhibited less anti-inflammatory activity, that is 57.88% and 60.6 1% respectively at the end of 3 hrs. The activity obtained was comparable to that of marketed oral and topical preparations of Diclofenac salts, a prototype of a non-steroidal anti-inflammatory agent.

Page(s): 159-163

DOI: DOI not available

Published: Journal: Hamdard Medicus, Volume: 50, Issue: 3, Year: 2007

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