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An efficient catalyst for the synthesis of schiff bases.
Author(s):
1. Ghulam-Fareed: Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Karachi, Pakistan; Department of Chemistry, Federal Urdu University of Arts, Science and Technology, Karachi, Pakistan
2. Muhammad Ali Versiani: Department of Chemistry, Federal Urdu University of Arts, Science and Technology, Karachi, Pakistan
3. Nighat Afza: Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Karachi, Pakistan
4. Nazia Fareed: Department of Chemistry, Federal Urdu University of Arts, Science and Technology, Karachi, Pakistan
5. Mahboob Ali Kalhoro: Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Karachi, Pakistan
6. Shazia Yasmeen: Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Karachi, Pakistan
7. Muhammad Aijaz Anwar: Pharmaceutical Research Center, PCSIR Laboratories Complex Karachi, Karachi, Pakistan
Abstract:
An efficient high yielding synthesis of Schiff bases (1-17) is derived from condensation of 2-fluorenamine and 4-amino phenol with a variety of aldehydes catalyzed by dodecatungstosilicic acid / P2O5 under solvent free conditions at room temperature. The catayst is found to be more efficient in terms of ease of reaction workup and high yields. This methodology contributes to an energy efficient, facile and environamental friendly synthesis for the preparation of Schiff bases. The structures of afforded Schiff bases were characterized by spectroscopic data and elemental analysis.
Page(s): 427-431
DOI: DOI not available
Published: Journal: Journal of Chemical Society of Pakistan, Volume: 35, Issue: 2, Year: 2013
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