Variation in the Genetic Effects of Abcg2, Growth Hormone and Growth Hormone Receptor Gene Polymorphisms on Milk Production Traits in Egyptian Native, Holstein and Hybrid Cattle Populations. | [Pakistan Veterinary Journal • 2018]

Author(s):

1. AF ElNahas: Department of Animal Husbandry and Animal Wealth Development, Faculty of Veterinary Medicine, Alexandria University, Egypt

2. WM Basiony: Department of Animal Wealth Development, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt

3. S ElKassas: Animal, Poultry and Fish Breeding and Production, Department of Animal Wealth Development, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt

4. S Mahmoud: Department of Physiology, Faculty of Veterinary Medicine, Kafrelsheikh University, Egypt

Abstract:

The aim of the present study was to evaluate the effect of polymorphisms in the ATP-binding cassette subfamily G member 2 (ABCG2), growth hormone (GH) and growth hormone receptor (GHR) genes on 305-day yields and milk traits in native Egyptian cattle (Baladi), Holstein Friesian cattle and hybrid cattle using DNA sequencing and Restriction Fragment Length Polymorphisms (RFLPs). A total of 148 cows were selected from the three animal populations. The ABCG2-HhaI-AA genotype was significantly associated with an increased milk lactose percentage and reduced milk yields in Baladi cows. The GH-MSP1-heterozygous genotype (GH) showed significant associations with SNF, protein and lactose percentages in the hybrid cows. Fewer TG repeats were found in the 5' untranslated region of GHR in Baladi cows, which could be used for marker-assisted selection to protect against the lower milk yields observed in this population. Additionally, GHR-MSP1-VL, can be associated with higher SNF, fat, protein and lactose percentages in hybrid cows, as well as lower milk yields in Baladi cows. We concluded that the three cattle populations have their own genetic identities in relation to genetic markers, which can be used for marker-assisted selection to improve milk traits in these three cattle populations.

Page(s): 371-376

DOI: 10.29261/pakvetj/2018.089

Published: Journal: Pakistan Veterinary Journal, Volume: 38, Issue: 4, Year: 2018

Keywords:

Cattle Marker assisted selection Milk traits Polymorphism RFLPs

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