Visualisation of medullary carcinoma thyroid with locally formulated "mtc (v) dms and comparison with ^i-mibg scintigraphy | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2001]

Author(s):

1. Aakif Ullah Khan: Department of Nuclear Medicine, Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan.

2. Shakil Ahmad: Department of Nuclear Medicine, Larkana Institute of Nuclear Medicine and adiotherapy (LINAR), Larkana Pakistan

3. Amjad Aziz Khan: Department of Nuclear Medicine, Institute of Radiotherapy and Nuclear Medicine (IRNUM), Peshawar, Pakistan.

Abstract:

Technetium-99m (pentavalent) dimercaptosuccinic acid (99mTc (V) DMS) scintigraphy was performed in one patient with histopathologically confirmed medullary carcinoma thyroid (MCT) using a locally formulated kit. Marked uptake of the tracer by the primary and locally metastatic sites was noted. The same patient was also subjected to lodine-131-metaiodobenzoilguanidine (13i|-MIBG) scintigraphy and the results were found comparable. Better resolution, easy in-house formulation, labelling with 99mTc (V) DMS makes it a better imaging agent as compared to 13i|-MIBG for the imaging of the primary and metastatic medullary carcinoma thyroid in our setup. Furthermore, the formulation of 99mTc (V) DMS is simple and convenient procedure

Page(s): 394-396

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 11, Issue: 6, Year: 2001

Keywords:

Scintigraphy Radionuclide imaging Technetium compounds Iodine radioisotopes Thyroid neoplasms Carcinoma , medullary

References:

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[3] Fogelman ,Maisey MN,Clark SEM .1994 .. Tumour In: An atlas of clinicanluclearmedicine. 2 ed. London Martin Dunitz, : 267.

[4] Clarke SEM,Wrarght P,Michael J,Gelfand J,Abdelhamid H,Elgazzar H .1994 .-123 MIBG SPECT versus [99mTc]MDP-an evaluationof threeimaging tech plana rimaging in childrenwith neuralcrestumors. niques in patientswith medullarcyarcinomaof the JNudMed, 35 : 1753-7.

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