Abstract:
Objective: To investigate the e ect of the uid challenge test on the optic nerve sheath diameter (ONSD) change. Study Design: Quasi-experimental study. Place and Duration of Study:Department of Anesthesiology and Reanimation, Ondokuz Mayis University Hospital, Samsun, Turkey, from January to November 2021. Methodology: A uid challenge was de ned as a 500 mL crystalloid infusion administered over 10 minutes, and uid responsiveness was de ned as a subsequent increase in stroke volume of at least 15% administered to the ICU patients. The ONSD and hemodynamic variables were measured by ultrasonography before T(0), at the end (T1), and 30 min after the uid challenge (T2). The primary outcome of the study was the change in ONSD measurements associated with the uid challenge, and the secondary outcome was the relationship between uid responsiveness and the change in ONSD. Results: A total of 60 patients were included. The ONSD (mm) value was signi cantly higher atT1 compared to T0 (mean ± standard deviation: 5.12±0.30 mm vs. 5.10±0.32 mm; p=0.011). However, atT2, the ONSD was similar to that atT0 (5.10±0.31 mm vs. 5.10±0.32 mm; p=0.662). The stroke volume (mL) was also signi cantly higher at T1 and T2 compared to T0 [median IQR 60 (6) mL vs. 60 (4.7) mL vs. 52 (5) mL, respectively, p <0.01]. No signi cant relationship was found between the ONSD and the change in uid responsiveness (p=0.621). Conclusion: The uid challenge test increases ONSD and may cause an increase in intracranial pressure.
Page(s):
1116-1121
DOI:
DOI not available
Published:
Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 32, Issue: 9, Year: 2022
Keywords:
Optic nerve sheath diameter
,
fluid therapy
,
Ultrasonography
,
Stroke volume
,
Intracranial Pressure