A comparative study on the efficacy of robot of stereotactic assistant and frame-assisted stereotactic drilling, drainage for intracerebral hematoma in patients with hypertensive intracerebral hemorrhage | [Pakistan Journal of Medical Sciences • 2022]

Author(s):

1. Liang Liang: Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding, 071000, Hebei, China.

2. Xin Li: Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.

3. Haiqing Dong: Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.

4. Xin Gong: Department of Neurosurgery, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.

5. Guanpeng Wang: Department of Neuroscience Critical Care Unit, Baoding No.1 Central Hospital, Baoding 071000, Hebei, China.

Abstract:

Objectives: To compare the clinical efficacy of robot of stereotactic assistant (ROSA) and frame-assisted stereotactic drilling and drainage for intracerebral hematoma in hypertensive intracerebral hemorrhage (HICH). Methods: A total of 142 patients with HICH treated in Baoding First Central Hospital from January 2018 to January 2020 were selected and divided into two groups using a random number table. The ROSA group was treated with a robot of stereotactic assistant, while the frame group underwent frame-assisted stereotactic drilling and drainage for intracerebral hematoma. Surgical duration, postoperative extubation time and complications were compared between the two groups. Venous blood (5 mL) was collected before and three days after surgery. The levels of inflammatory factors [tumor necrosis factor-a (TNF-a), highsensitivity C-reactive protein (hs-CRP) and interleukin-6 (IL-6)], as well as neurological function indexes [neuron-specific enolase (NSE), nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF)] were detected by enzyme-linked immunosorbent assay. Results: The surgical duration, postoperative extubation time, and incidences of infection and postoperative rehemorrhage in the ROSA group were lower than those in the frame group (P < 0.05). In the ROSA group, postoperative TNF-a, hs-CRP, IL-6 and NSE levels were significantly lower while NGF and BDNF levels were higher than those in the frame group (all P < 0.05). Conclusion: Compared with frame-assisted stereotactic drilling and drainage for intracerebral hematoma, ROSA in HICH treatment shortens the surgical duration and postoperative extubation time, reduces the risks of infection and rehemorrhage and decreases inflammatory level, which is helpful for the recovery of neurological function.

Page(s): 1796-1801

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical Sciences, Volume: 38, Issue: 7, Year: 2022

Keywords:

efficacy , Hypertensive intracerebral hemorrhage , Robot of stereotactic assistant , Stereotactic frame

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