Abstract:
OBJECTIVES: To observe and assess the efficacy of Aloe Vera extract on skin wound healing. STUDY DESIGN:Analytic and experimental. PLACE AND DURATION: Departments of Physiology, Pathology and Postgraduate Research Lab of ISRA University Hyderabad, from June 2011 to December 2011. METHODOLOGY: 20 millimeter long cuts were made over the back of 18 rabbits. The rabbits were divided into three groups A,B & C, each comprising 06 numbers, & treated daily for 11 days with Xylo Aid, mixture of Xylo Aid & Alo Vera extract and Aloe Vera extract, and marked blue, black & green respectively. Taking the operation day as zero, 3 rabbits were sacrificed after 24 hours and then alternatively till the 11th post-operative day. The entire wound area along with 4-5 mm of the surrounding skin was excised and fixated in 10% formaldehyde, after processing sections were made stained with H&E & observed under microscope, the fibroblasts were counted to see the quality of wound healing, keeping group A as control the results were tabulated. RESULTS: Visual observation showed that by 11th day post wounding the recovery was 75% approximately with Aloe Vera extract application, 50% and 30% was observed with mixture application and Xylo Aid respectively. CONCLUSION: Aloe Vera application for 11 days on rabbit skin wound showed better healing process in comparison to mixture and Xylo Aid.
Page(s):
198-199
DOI:
DOI not available
Published:
Journal: Isra Medical Journal, Volume: 5, Issue: 3, Year: 2013