Acute Necrotizing Encephalopathy of Childhood: a Fatal Complication of Swine Flu | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2011]

Author(s):

1. Muhammad Rehan Khan: Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan

2. Prem Kumar Maheshwari: Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan

3. Syed Asad Ali: Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan

4. Anwarul Haque: Department of Paediatrics, The Aga Khan University Hospital, Karachi, Pakistan

Abstract:

Acute necrotizing encephalopathy of childhood (ANEC) is a rare condition characterized by the presence of multifocal symmetrical brain lesions involving mainly thalami, brainstem, cerebellum and white matter. ANEC is a serious and life threatening complication of simple viral infections. We present a case of a young child who developed this condition with classical clinical and radiological findings consistent with ANEC, secondary to swine flu (H1N1). He needed ventilatory support and had profound motor and intellectual deficit on discharge. We report this case with aim of raising awareness about this fatal complication of swine flu which has become a global health care issue these days

Page(s): 119-120

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 21, Issue: 2, Year: 2011

Keywords:

Acute necrotizing encephalopathy Children Swine flu Symmetrical brain lesions Thalami Brainstem Cerebellum White matter

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