A review of available herbal medicine options for the treatment of chronic insomnia | [Pakistan Journal of Medical and Health Sciences • 2021]

Author(s):

1. ZOHREH POURSALEH: School of Traditional Medicine, Shahid Beheshti University of Medical Sciences,Tehran,Iran

2. MAHMOOD KHODADOOST: Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

3. ENSIEH VAHEDI: Systems Biology and Poisonings Institute, Baqiyatallah University of Medical Sciences,Tehran,Iran

4. MOHAMMAD MAHDI AHMADIAN-ATTARI: Alborz University of Medical Sciences, Karaj, Iran

5. MAHDI JAFARI: Department of Clinical Psychology, School of Medicine, Shahid Beheshti University of Medical Sciences,Tehran,Iran

6. ERFAN POURSALEH: Faculty of Medicine, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran; Researchers and Elite Club, Tehran Medical Sciences, Islamic Azad University, Tehran, Iran *

Abstract:

Background: Insomnia is a universal health problem that affects the health and quality of life of people worldwide. During the last decade treatment of insomnia with herbal has been introduced to be effective but unfortunately, the safety and efficacy of these medicines are currently uncertain. However, the administration of various herbal medicines for insomnia is increasing mainly due to the diversity of various adverse effects of western medication. Objective: The present study is aimed to investigate available herbal medicine options for the treatment of chronic insomnia. Method: All demanded data were retrieved from electronic databases, Natural Medicines, TCMID, Natural Medicines Comprehensive Database, MedlinePlus, PubMed, EMBASE, and Google Scholar. Among them, randomized clinical trials were chosen precisely to be investigated more for seeking any additional information related to the treatment of chronic insomnia. All related papers in English and Persian languages included in the study criteria. At first, 162 articles were chosen to be investigated, then after screening all articles based on the PRISMA method, 83 qualified articles remained to be investigated carefully. Results: Herbal plants with medical properties as sedative agents are obtaining more and more attention because they contain various types of natural bioactive metabolites with the lowest rate of adverse effects. Moreover, these novel medicines are highly economic, with high efficacy while could be available easily. Conclusion: The data from this study demonstrated that medical plants could yield sedative activity and some of them are effective for insomnia, but we must not forget that further clinical trials are demanded to approve this.

Page(s): 1589-1598

DOI: 10.53350/pjmhs211551589

Published: Journal: Pakistan Journal of Medical and Health Sciences, Volume: 15, Issue: 5, Year: 2021

Keywords:

Herbal medicine , Sleep disorders , treatment , Chronic insomnia , Alternative medication

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