A comprehensive review on gout: The epidemiological trends, pathophysiology, clinical presentation, diagnosis and treatment | [Journal of Pakistan Medical Association • 2021]

Author(s):

1. Kanwal Ashiq: Department of Pharmaceutical Sciences, Superior College, Superior University, Lahore,Pakistan

2. Mayyda Asif Bajwa: Department of Applied Molecular Biology, University of the Punjab,Lahore,Pakistan

3. Samreen Tanveer: Department of Applied Molecular Biology, University of the Punjab,Lahore,Pakistan

4. Mehwish Qayyum: Department of Pharmaceutical Sciences, Superior College, Superior University, Lahore,Pakistan

5. Sana Ashiq: Department of Applied Molecular Biology, University of the Punjab,Lahore,Pakistan

6. Rabia Khokhar: Department of Pharmaceutical Sciences, University of Veterinary and Animal Sciences,Lahore,Pakistan

7. Farah Abid: University of Lahore,Lahore,Pakistan

Abstract:

The current review was planned to assess updated knowledge about gout and to highlight the various areas which need to be focussed upon for better healthcare. Relevant articles published in English language were reviewed by utilising various databases including Google Scholar, Springer Link, Science Direct and MEDLINE. Data revealed a precipitating number of gout cases from the developed countries, while the developing countries on the other hand were found to be faced with an even higher threat. The risk factors and pathophysiology of gout are immaculate and clearly established. Hence, appropriate measures can be explored and worked on to pinpoint diagnosis, and economical treatment. In order to lessen the elevated global health burden along with revolutionising the patient's quality of life, an immediate action is required in certain aspects, like the adoption of a healthy modified lifestyle, a reduction in exposure to risk factors, robust prophylactic measures, bettering awareness, and an approach to early diagnosis followed by optimal treatment protocols.

Page(s): 1234-1238

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 71, Issue: 4, Year: 2021

Keywords:

Allopurinol , inflammation , Gout , Xanthine oxidase

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