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Adamantyl group as medicinal agent Part I; Preparation of some adamantane derivatives.
Author(s):
1. Mahbub Alam: Faculty of Pharmacy, University of Punjab, Lahore, Pakistan
2. M. Amin: Faculty of Pharmacy, University of Punjab, Lahore, Pakistan
Abstract:
Some of the tertiary mono-substituted derivatives of adamantane have been prepared by convenient routes e.g. conversion of 1-bromo adamantane with Me-CN/H2SO4 to 1-acetamide derivative which on hydrolysis afforded 1-amine adamantane. 1-Bromo derivative has been obtained from bridgehead halogen exchange. Carboxy, chloro and hydroxy derivatives have also been prepared.
Page(s): 53-57
DOI: DOI not available
Published: Journal: Pakistan journal of scientific research, Volume: 30, Issue: 1--4, Year: 1978
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