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An update on the pathophysiology and pharmacology of Alzheimers disease.
Author(s):
1. Touqeer Ahmed: Atta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, Pakistan
Abstract:
Alzheimers disease (AD) is a progressive neurodegenerative disease. Plaques and tangles are described as the characteristics features of AD, which are neurotoxic entities, deposited in the diseased patients. There are very few drugs available for the treatment of AD. Those available options are primarily the approaches to overcome cholinergic hypofunction, through the inhibition of acetylcholinesterase enzyme. Other disease modifying candidates are strongly needed to overcome the progressive dementia in AD. These new drugs will serve as a great hope for the AD patients and families of the AD patients.
Page(s): 38-43
DOI: DOI not available
Published: Journal: NUST Journal of Natural Sciences, Volume: 2, Issue: 2, Year: 2012
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