Author(s):
1. Hamid Shafiq:
Department of Biochemistry & Molecular Biology, Army Medical College, National University of Sciences and Technology,Islamabad,Pakistan
2. Asifa Majeed:
Department of Biochemistry & Molecular Biology, Army Medical College, National University of Sciences and Technology,Islamabad,Pakistan
Abstract:
Background: Vitamins are organic compounds that play significant role in management of metabolic processes. Vitamin D is considered a nutrient associated with a bio-signalling action. It has vital participation in constant maintenance of calcium level in both intra and extracellular body fluids. The present study analyzed the vitamin D and PTH levels in Punjabi population of Pakistan. Methods: This was a cross-sectional observational study. Sample collection was done from Oct 2017 to Oct 2018 from various local health facilities of Punjab, and blood samples of 400 subjects were collected. The quantitative measurement of vitamin D was obtained by automated competitive chemiluminescence immunoassay method. PTH levels were calculated by direct Chemiluminescence kit. The values of vitamin D thus obtained were compared with levels of parathyroid hormones along within different age groups. Results: Overall 77.5% of studied population was deficient/insufficient of vitamin D. Thirtyfive percent individuals in age group up to 20 years, and 88.8% in age group 21-40 years were deficient/insufficient. In age group 41-60 years, 115 out of 120 (95.8%) people showed deficiency/insufficiency. On comparison of vitamin D with parathyroid hormone levels a significant (p<0.001) negative association was observed. Our study is in agreement with others that demonstrate a high prevalence of cholecalciferol deficiency in many populations. Conclusion: Cross-sectional study measurement of Vitamin D is of paramount importance in our population. Timely correction of its deficiency can ward off many complications resulting from its direct and indirect effects.
Page(s):
7-10
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Physiology, Volume: 15, Issue: 2, Year: 2019
Keywords:
Pakistan
,
Age factor
,
Vitamin D
,
Bone Mineral
,
Parathyroid hormone
,
Deficiency
,
PTH
References:
References are not available for this document.
Citations
Citations are not available for this document.