Abstract:
Bees produce propolis by mixing tree gum collected from young leaves, flowers, and stems with salivary enzymes. Honeybees use it mainly as a sealant and disinfectant. Due to its antioxidative properties, propolis reduces the risk of cardiovascular diseases. Some components of propolis, especially cinnamic derivatives (caffeic acid and caffeic acid phenyl ester) and flavonoids (quercetin and naringenin), have adverse effects on the bacterial cell membrane, decrease motility and prevent the formation of biofilms by gram-positive bacteria. Ethanol extract of propolis inhibits the urease activity produced by Helicobacter pylori and may prevent gastrointestinal diseases. Pinocembrin is one of the components of propolis that affects mold. Propolis inhibits hyphal cell respiration, which leads to energy depletion and cell membrane damage, and accelerates cell death. The mechanism of action of propolis on yeasts is related to the disruption of the cell wall instead of affecting membrane permeability. The antiviral activity of propolis is due to flavonoids, caffeic acid, and aromatic acid esters. It prevents proliferation, blocks the virus transmission to other cells, and destroys the virus’s outer covering. Propolis is effective against polio, influenza A and B, as well as against HSV-1 and HSV-2 viruses. Therefore, as a natural compound with antioxidant, antibacterial, antiviral, and antimicrobial properties, propolis may heal wounds, cardiovascular, and stomach ulcers. However, more clinical studies are needed to support propolis's antioxidant, antimicrobial, and antiinflammatory activity.
Page(s):
8-8
DOI:
DOI not available
Published:
Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
Propolis
,
antimicrobial activity
,
Cardiovascular
,
antiviral activity