Toxic effect of Insecticides Mixtures on Antioxidant Enzymes in Different Organs of Fish, Labeo rohita. | [Pakistan Journal of Zoology • 2019]

Author(s):

1. Huma Naz: Department of Zoology, Cholistan University of Veterinary and Animal Sciences, Bahawalpur, Pakistan

2. Sajid Abdullah: Department of Zoology, Wildlife and Fisheries, University of Agriculture, Faisalabad, Pakistan

3. Khalid Abbas: Department of Zoology, Wildlife and Fisheries, University of Agriculture, Faisalabad, Pakistan

4. Wardah Hassan: Department of Zoology, University of Sargodha, Sargodha, Pakistan

5. Moazama Batool: Department of Zoology, Govt. College Women University, Sialkot, Pakistan

6. Shakeela Perveen: Department of Zoology, Govt. Sadiq College Women University, Bahawlpur

7. Sadia Maalik: Department of Zoology, Govt. College Women University, Sialkot, Pakistan

8. Sajida Mushtaq: Department of Zoology, Govt. College Women University, Sialkot, Pakistan

Abstract:

In this study insecticides toxic effects of mixture of organochlorine (endosulfan) and organophosphate (chlorpyrifos) investigated on the activity of antioxidant enzymes viz. superoxide dismutase, peroxidase, catalase and glutathione S-transferase in different organs (liver, gills, kidney, brain, heart and muscle) of fish, Labeo rohita. The LC50 of chlorpyrifos+endosulfan mixture was calculated as 1.95±0.02 µgL-1 for 96 h with the 95% confidence limits. The fish expose to the mixture (1:1) for 96-h. The results obtained from this study showed that superoxide dismutase, peroxidase and glutathione S-transferase activities in the liver, gills, kidney, brain, heart and muscle were significantly (P<0.05) increased compared to control. The superoxide dismutase activity in organs of fish followed the order: liver>brain>kidney>gills>heart>muscle. The mean peroxidase activity in L. rohita followed the pattern: liver>brain>gills>kidney>heart>muscle. The glutathione S-transferse activity followed the order: brain>muscle>liver>gills>kidney>heart. However, catalase activity was significantly (P<0.05) increased in liver, gills and kidney of pesticides mixture exposed L. rohita as compared to control while it was decreased in brain, heart and muscle.

Page(s): 1355-1361

DOI: 10.17582/journal.pjz/2019.51.4.1355.1361

Published: Journal: Pakistan Journal of Zoology, Volume: 51, Issue: 4, Year: 2019

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