To compare efficacy between cryotherapy and mitomycin microneedling for the treatment of plantar warts | [Journal of Ayub Medical College • 2023]

Author(s):

1. Faheema Afsar Khan: College of Physicians & Surgeons of Pakistan(CPSP), Islamabad, Pakistan

2. Majid Hussain: National University of Medical Sciences,Rawalpindi-,Pakistan

3. Bushra Muzaffar Khan: National University of Medical Sciences,Rawalpindi-,Pakistan

4. Saima Afsar: National University of Medical Sciences,Rawalpindi-,Pakistan

5. Mairah Shafique: National University of Medical Sciences,Rawalpindi-,Pakistan

6. Sami Ul Haq: College of Physicians & Surgeons of Pakistan(CPSP), Islamabad, Pakistan

7. Nadia Akbar: College of Physicians & Surgeons of Pakistan(CPSP), Islamabad, Pakistan

8. Adeel Siddique: National University of Medical Sciences,Rawalpindi-,Pakistan

Abstract:

Background: Cryotherapy is a common destructive treatment modality for treating plantar warts that results in blistering and scarring. Mitomycin an antitumor drug with antiviral property is a safe, better and a promising option for treating plantar warts. Objective was to compare efficacy of cryotherapy and mitomycin microneedling in the management of plantar warts. It was a randomized controlled trial conducted at the Skin Department CMH Abbottabad from 1st May to 31st December 2021. Methods: The study included 60 patients with plantar warts. Each group with 30 patients. Random tables were used to determine the distribution of patients within each group. Group A received mitomycin microneedling (1u/ml) repeated every 3 weeks. Group B was prescribed liquid nitrogen cryotherapy. The freeze-thaw cycle was 20 secs and repeated every 2 weeks. Both groups were treated for 4 months duration. For analysis of data, SPSS version 21.0 was used. Efficacy was compared by the application of Chi-square test between the two groups. p<0.05 was considered statistically significant. Results: Mitomycin microneedling completely cured 76.7% of patients, while cryotherapy was effective for only 56.7%. Complete remission was observed after two to three sessions of mitomycin microneedling while average of 4 sessions of cryotherapy were required for complete remission. In general, microneedling with mitomycin had better tolerance, pain being the commonest adverse effect. Conclusion: Plantar warts can be effectively treated with mitomycin microneedling. Treatment of plantar warts with this method is more effective, requires fewer sessions, and may take less time to complete.

Page(s): 133-136

DOI: 10.55519/JAMC-01-10932

Published: Journal: Journal of Ayub Medical College, Volume: 35, Issue: 1, Year: 2023

Keywords:

cryotherapy , microneedling , Mitomycin , Plantar wart

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