Abstract:
To find out the association of tobacco as a contributory factor in patients presenting with peptic ulcer disease (PUD). A descriptive case study was conducted at the department of Medicine, Postgraduate Medical Institute, Lady Reading Hospital, Peshawar, from May 2001 to April 2002. A total number of 100 consecutive patients, 76 male and 24 females, with endoscopically proven peptic ulcer were enrolled in the study. The ages of the patients ranged from 25 to 70 years; with mean age of 48 years ± 12.26 standard deviations, (mean age of men 49 years ± 12.88 SD, and mean age of woman 45 years ± 9.67 SD). All the patients underwent endoscopy after an overnight fast, using lignocaine (4% solution or jelly) as topical anaesthetic, with Pentax FG29 video-endoscope. Fifty-six percent of all the patients with PUD used tobacco, 33% as cigarette, 18% took it as ‘naswar’ and 5% of patients used it in both forms. Of these, 85.7% (48/56) patients had duodenal ulcer and 14.3% (8/56) patients had gastric ulcer. All these patients were male, none of the female patients used tobacco in any form. Moreover, 40% of PUD patients reported long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). This study supports the view that use of tobacco is associated with PUD in men.
Page(s):
385-387
DOI:
DOI not available
Published:
Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 13, Issue: 7, Year: 2003