The prevalence of the Hepatitis B virus among Sudanese pregnant women in El Obeid, North Kordofan | [Bioscience Research • 2024]

Author(s):

1. Eldaw Breima Suliman Mohamed: Microbiology Department, Faculty of Medical Laboratory Sciences, University of Kordofan, 2 Shikan College of Medicine, El-Obeid, Sudan; Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan, Sudan

2. Mnasek Ibrahim Mohammed: Microbiology Department, Faculty of Medical Laboratory Sciences, University of Kordofan, 2 Shikan College of Medicine,El-Obeid,Sudan

3. Haitham Abdalla Ali Ismail: Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan,,Sudan

4. Samira Mekki Ahmed Ali: Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan,,Sudan

5. Mohammed Adam Mohammed Ali: Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan,,Sudan

6. Ahmed Elnour Adam Zakaria: Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan,,Sudan

7. Ahmed Kbbashi Sulieman Sharf Eldien: Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan,,Sudan

8. Ahmed Amin Mohammed: Obstetrics and Gynecology Department, Faculty of Medicine, University of Kordofan,,Sudan

9. Mohamed Ahmed Agab: Internal Medicine Department, Faculty of Medicine, University of Kordofan, Sudan

10. Hussain Gadelkarim Ahmed: Department of Histopathology and Cytology, University of Khartoum, Sudan

Abstract:

Background: Hepatitis B (HBV) is a global public health issue, with millions of people developing chronic infections. This study examined HBV prevalence and risk factors in three-trimester pregnant women at the Sudan Family Planning Association (SFPA) and El Obeid Teaching Hospital. From January to July 2023, pregnant women attending Sudan Family Planning Association and El Obeid Teaching Hospital's Obstetrics and Gynecology departments participated in a hospital-based cross-sectional survey. A standardized questionnaire was used to collect socio-demographic data and HBV risk factors from 226 pregnant women, with a 98.2% response rate. Each trial participant gave five mL of venous blood. Screening HBsAg Rapid HbsAg testing was done, and ELISA (ToshoAIA900) verified the positive result. Most pregnant women (31.4%) were 21-25 years old. Most participants, 125 (55.3%), were urbanites, and most women, 107 (47.3%), had multiple births. Overall HBV prevalence was 11 (4.87%). HBV prevalence was high (45.4%) among 26-30year-olds, urban (76.3%), and pregnant women with >2 birth frequencies. No statistically significant association was found between HBV infection and risk factors for transmission (history of surgical procedure, dental extraction, gestational age from first to third trimesters, history of abortion and blood transfusion, history of jaundice, and hepatitis B vaccination). The overall HBV prevalence was 4.87%. This HBV prevalence in pregnant women shows intermediate WHO HbsAg endemicity. This study demonstrated no significant association between sociodemographic and predicted risk factors for HBV infection, except for age. We found immunization effective as a preventative approach.

Page(s): 314-320

DOI: DOI not available

Published: Journal: Bioscience Research, Volume: 21, Issue: 2, Year: 2024

Keywords:

Prevalence Hepatitis B virus , Elobeid Sudan , Three Trimester Pregnant Women

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