Abstract:
Gestational diabetes mellitus, more commonly known as GDM, is a frequent pregnancy condition. It carries significant short-term and long-term adverse health outcomes for both the mother and the offspring. The physiological alterations in insulin resistance and lipid profiles are accentuated in GDM women, which may reflect an underlying metabolic abnormality that only temporarily presents itself during pregnancy. An example of the hyperglycemic intrauterine environment is provided by pregnancies that are complicated by gestational diabetes mellitus. This environment may not only reflect but also drive the epidemic of type 2 diabetes mellitus (T2DM). Supplementation with probiotics has the ability to reduce GD-predisposing metabolic parameters such blood glucose level, lipid profile, inflammation, and oxidative indicators, which in turn may reduce the incidence of GD in pregnant women. Remarkable outcomes have been seen by the supplementation of probiotic strains during pregnancy. In addition to lowering lipid profiles, inflammatory markers, and oxidative stress, probiotics were found to have favorable impacts on gene expressions related to insulin, inflammation, and glycemic management. By generating changes in the microbiota of the gut, probiotics may help women maintain a healthy weight and experience fewer difficulties during pregnancy. It's possible that probiotics could have an effect on the microbiota of an infant, which would have significant repercussions for the child's growth and health. Following on from the previous point, probiotic supplementation lowers the risk of GD in pregnant women. As a result, the administration of particular probiotics through supplementation could be considered one of the adjuvant therapies for patients suffering from GD.
Page(s):
11-11
DOI:
DOI not available
Published:
Journal: International Food & Nutrition Conference" August 18th-20th, 2022, University of Swat, Swat (Book of Abstracts), Volume: 1, Issue: 1, Year: 2022