Using intranasal corticosteroids and oral antihistamines to treat allergic rhinitis: a comparison of the mean total nasal symptom score | [Annals of Punjab Medical College • 2023]

Author(s):

1. Arshad Ullah Afridi: Department of ENT, Shalamar Medical & Dental College/Shalamar Hospital, Lahore Pakistan

2. Rabia Zaman Khan: Department of ENT Unit I, Fatima Jinnah Medical University, Lahore Pakistan

3. Umair Wahab: Fatima Jinnah Medical University / Sir Ganga Ram Hospital, Lahore Pakistan

4. Ali Nasir: Department of ENT, Fatima Memorial Hospital, Lahore Pakistan

5. Zanib Javed Chatha: Department of ENT, Shalamar Hospital, Lahore Pakistan

6. Sarwat Iqbal: Department of Medicine, Shalamar Medical & Dental College/ Shalamar Hospital, Lahore Pakistan

Abstract:

Background: Allergic rhinitis (AR) is a global public health issue. The disease is a leading cause of death and disabilities globally. Objective: To compare the mean total nasal symptom score using intranasal corticosteroids with oral antihistamine in management of allergic rhinitis. Study Design: Randomized controlled trial. Settings: Department of ENT, Shalamar Medical and Dental College/ Shalamar Hospital, Lahore Pakistan. Duration: 1st January 2023 to 30 June 2023. Methods: 100 cases equally divided in two groups A&B, Intranasal corticosteroids were administered in Group A and oral anti-histamine in Group B cases, The final evaluation was done after 4 weeks of treatment. Results: Comparison of mean total nasal symptom score using intranasal corticosteroids with oral anti-histamine in management of allergic rhinitis shows that 1.51 ± 0.37 score in Group-A and 1.27 ± 0.11 score in Group-B, (p-value < 0.05). Conclusion: We found that the use of intranasal corticosteroids resulted in a substantially reduced mean total nasal symptom score compared to the use of oral anti-histamine in the treatment of allergic rhinitis.

Page(s): 358-360

DOI: 10.29054/APMC/2023.1449

Published: Journal: Annals of Punjab Medical College, Volume: 17, Issue: 3, Year: 2023

Keywords:

Management , allergic rhinitis , Intranasal corticosteroids , Oral antihistamine , Total nasal symptom score

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