Widespread verruca vulgaris on plaque psoriasis lesions: an uncommon clinical presentation | [Journal of Pakistan Association of Dermatologists • 2023]

Author(s):

1. Rusdin Isnain Makbul: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

2. Nurul Rezki Fitriani Azis,: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

3. Suci Budhiani,: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

4. Nurelly Waspodo: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

5. Faridha Ilyas: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

6. Farida Tabri: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

7. Sri Rimayani Malik: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

8. Andi Hardianty: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

9. Khairuddin Djawad: Department of Dermatology and Venereology, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia

Abstract:

Psoriasis is a common, chronic, recurrent, immune-mediated disease that leads to dysregulation of epidermal proliferation. Plaque psoriasis is the most common psoriasis variant characterized with pruritic, well-defined erythematous plaques accompanied with thick silvery scales. Widespread lesions may require long-term immunosuppressive treatments that can lead to certain opportunistic infections such as verruca vulgaris. The role human papillomavirus (HPV) in psoriatic skin lesions is still unclear. It is thought that HPV is associated with the precipitation of psoriatic lesions. We report a case of a 65-year-old male patient with severe plaque psoriasis with an uncommon clinical presentation of widespread verruca vulgaris overlapping the psoriasis lesions thought to be caused by long-term treatment of methotrexate, prompting physicians to be more aware of the potential complications of using immunosuppressants for the management of various immunological diseases.

Page(s): 787-790

DOI: DOI not available

Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 33, Issue: 2, Year: 2023

Keywords:

Methotrexate , Abstract , verruca vulgaris , eolgtPsoriasis vulgaris , Overlapping

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