Author(s):
1. Arwa Flemban:
Pathology Department, Faculty of Medicine, Umm Al-Qura University,Makkah, Kingdom of,Saudi Arabia
Abstract:
Herein, a case for histiocytic sarcoma, a rare aggressive type of sarcoma, of a Saudi male patient is presented. NextGen sequencing (NGS) was utilized to assess for mutations in an ethylenediamine tetraacetic acid (EDTA) blood sample of the patient that revealed nine rare variants for three genes namely PIK3CA (phosphatidylinositol-4, 5-bisphosphate,3-kinase catalytic-subunit a; KRAS(Kirsten rat sarcomaviral oncogene-homolog); and TP53(tumor protein-p53). This insight into this case can shed a light on potential genes that play impact in pathogenesis/progression of this rare case.
Page(s):
603-605
DOI:
DOI not available
Published:
Journal: International Journal of Biology and Biotechnology, Volume: 20, Issue: 4, Year: 2023
Keywords:
genetic characterization
,
molecular pathology
,
Histiocytic sarcoma
,
nextgeneration sequencing NGS
References:
References are not available for this document.
Citations
Citations are not available for this document.