Abstract:
Introduction and objectives: Asymptomatic bacteriuria (ASB) is defined as an urinary tract infection in which bacteria are present in the urine (>=105 CFU/ml) but the bacteria are not causing general or local symptoms of urinary infection. The present study was carried out in order to determine the incidence of asymptomatic bacteriuria in children of different age groups and sex, and to isolate the organism responsible for asymptomatic bacteriuria and to know their antimicrobial susceptibility pattern. Material and Methods: Mid-stream urine samples were collected in sterile bottles from 253 children aged 3 months through 12 years at the Taleghani hospital in the Abadan from the 1st July,2008 to 31 June,2009. Culture plates with bacteria counts >=105 CFU/ml were taken as positive. The bacteria isolates were identified based on colony morphology characteristics, Gram stain reaction and biochemical tests. The identified bacteria were then tested in vitro with standard antibiotics disc to determine their antibiotics sensitivity patterns. Results: It was found that 27(10.6%) cases of the 253 patients had asymptomatic bacteriuria. Of the 164 females examined, 21(12.8%) had positive urine culture while 6 (6.74%) of the 89 males had significant bacteriuria. The maximum isolates were E.coli 9(33.3%), followed by Staphylococcus saphrophyticus 6(22.2%) and Staphylococcus aureus 5(18.5%). The antibiotics sensitivity tests revealed a high level of resistant to cotrimoxazole, amoxicillin and cefazolin as more than 60% of the isolates were resistance to these. While most of isolates were sensitive to ofloxaxin and cefixime. Conclusion: In the present study, there was a steady increase in the incidence of asymptomatic bacteriuria in different age groups. It is also suggested that appropriate antimicrobial be administered to reduce the risk of multiple resistant organisms developing and the avert ineffectiveness of antibiotics. Prompt therapeutic intervention is also essential to prevent cases of asymptomatic UTI from becoming symptomatic with resultant damage.
Page(s):
13-16
DOI:
DOI not available
Published:
Journal: Pakistan Paediatric Journal, Volume: 35, Issue: 1, Year: 2011