The antioxidant effect of Morus alba leaves extract on kidney, testes, spleen and intestine of mice. | [Pakistan Journal of Zoology • 2015]

Author(s):

1. Mohamed A. Dkhil: Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia;Department of Zoology and Entomology, Faculty of Science, Helwan University, Egypt

2. Amira A. Bauomy: Department of Zoology and Entomology, Faculty of Science, Helwan University, Egypt;Department of Laboratory Sciences, College of Science and Arts at Rass, Qassim University, Saudi Arabia

3. Marwa S. M. Diab: Molecular Drug Evaluation Department, National Organization for Drug Control & Research, Giza, Egypt

4. Saleh Al-Quraishy: Department of Zoology, College of Science, King Saud University, Riyadh, Saudi Arabia

Abstract:

The current study aims at determining the antioxidant properties of Morus alba leaves extract (MLE) on various organs of mice. Forty male Swiss albino mice were divided into control group and three different groups which received three different doses of MLE orally for 10 days. The glutathione, nitrite/nitrate, malondialdehyde levels were estimated in kidney, testis, spleen and jejunum of adult male albino mice. Also, the levels of urea, creatinine and uric acid were determined in blood plasma of mice. The oral gavage of M. alba leaves extract induced a highly significant increment in glutathione level while it caused a highly significant reduction of nitrite/nitrate and malondialdehyde in all studied organs. In addition, blood urea nitrogen, creatinine and uric acid were improved. We speculated that, MLE scavenged the free radicals in different mice organs under investigation due to its antioxidant activity.

Page(s): 393-397

DOI: DOI not available

Published: Journal: Pakistan Journal of Zoology, Volume: 47, Issue: 2, Year: 2015

Keywords:

Keywords are not available for this article.

References:

References are not available for this document.

Citations

Citations are not available for this document.

Citations

Downloads

Views